1. Recent work in spiralian development has also discovered insightful mechanisms of asymmetric cell division . 2. Asymmetric cell division is integral during development.3. Numb protein signaling plays a key role in binary cell fate decisions following asymmetric cell divisions . 4. The term "'asymmetric cell division "'usually refers to such intrinsic asymmetric divisions 5. In " Drosophila melanogaster ", asymmetric cell division plays an important role in neural development. 6. In normal stem and progenitor cells, asymmetric cell division balances proliferation and self-renewal with Notch. 7. Conversely, asymmetric cell division is expected to result in parent and daughter cells with different INM profiles. 8. The neuroblast repeatedly undergoes this asymmetric cell division while the GMC continues on to produce a pair of neurons. 9. Another mutation in asymmetric cell divisions which are involved in tumor growth are loss-of-function mutations. 10. The first suggestion that loss of asymmetric cell division might be involved in tumorigenesis came from studies of Drosophila.
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